Differin

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Differin

£22.99

Pack size - 45g
Differin gel

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The brand supplied may vary.

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  • Differin Gel 45g £22.99
  • Differin Cream 45g £22.99
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Differin is a prescription only medication used to treat acne.

Pack size: 1 x 45g

Active ingredients: Differin gel and cream contains adapalene, which is a type of retinoid. Adapalene helps to regulate skin cell turnover and reduce inflammation, making it effective for treating acne.

Acne Treatment: It is specifically formulated for the treatment of acne. It helps to unclog pores, prevent new acne breakouts, and reduce the formation of comedones (blackheads and whiteheads).

Different Formulations: Differin is available in various formulations, including gel and cream. Differin Gel is recommended for oily or combination skin, while Differin Cream is more suitable for individuals with dry or sensitive skin.

Sun Protection: It can increase skin sensitivity to sunlight, so it is essential to use sun protection measures, such as wearing sunscreen and avoiding excessive sun exposure, while using the product.

Product Information Leaflet

Buy Differin online in UK

If you are looking to buy Differin Gel or Cream online in the UK, Online Chemist offers this option.

Purchasing Differin online provides a convenient way to access this acne treatment from the comfort of your own home. However, it is important to ensure that you choose a trustworthy and legitimate online source.

Buy here!

How does Differin work?

Differin works by targeting the underlying causes of acne and promoting healthy skin cell turnover. The active ingredient in Differin is adapalene, which is a synthetic retinoid.

Here’s how Differin works:

  1. Normalising Skin Cell Turnover: Adapalene helps regulate the process of skin cell turnover. It encourages the shedding of dead skin cells from the surface of the skin, preventing them from clogging pores and leading to the formation of comedones (blackheads and whiteheads).

  2. Unclogging Pores: Differin helps to unclog pores by preventing the accumulation of excess sebum (oil) and keratin (a protein) within the pores. This action reduces the risk of new acne lesions forming.

  3. Reducing Inflammation: Adapalene has anti-inflammatory properties that help to calm and reduce inflammation associated with acne. By decreasing inflammation, Differin can help alleviate redness and swelling caused by acne breakouts.

  4. Preventing the Formation of New Acne Lesions: By regulating skin cell turnover and preventing the clogging of pores, Differin helps prevent the formation of new acne lesions. It reduces the number of comedones and decreases the likelihood of new pimples developing.

  5. Overall Improvement of Acne: With regular and consistent use, Differin can lead to a visible reduction in acne lesions, including comedones, pimples, and inflammatory acne.

Who can use Differin gel /cream?

Differin is generally suitable for individuals who are seeking treatment for acne. However, there are certain considerations and recommendations regarding its use. Here’s an overview:

  1. Age: Differin is commonly used by individuals aged 12 years and older. It is important to follow the specific age recommendations provided by healthcare professionals or indicated on the product packaging.

  2. Acne Type: Differin is typically effective for treating mild to moderate forms of acne. This includes comedonal acne (blackheads and whiteheads) and inflammatory acne (pimples and papules). For severe or cystic acne, other treatment options may be more appropriate and a healthcare professional’s guidance is advised.

  3. Skin Sensitivity: Differin may cause skin dryness, redness, or irritation, especially during the initial stages of treatment. It is generally well-tolerated, but individuals with particularly sensitive skin may need to adjust the frequency or concentration of Differin or opt for the cream formulation, which is more moisturizing.

  4. Pregnancy and Nursing: If you are pregnant or breastfeeding, it is important to consult with a healthcare professional before using Differin. The safety of adapalene during pregnancy and breastfeeding has not been fully established, and a healthcare professional can provide guidance based on your specific situation.

  5. Medication Interactions: Inform your healthcare professional about any other topical or systemic medications you are using to avoid potential interactions. This includes other acne treatments, such as benzoyl peroxide or topical antibiotics.

Who should not use Differin?

While Differin is generally safe and well-tolerated for most individuals, there are certain cases where its use may not be recommended. Here are some instances where Differin should not be used or used with caution:

  1. Allergy or Hypersensitivity: If you have a known allergy or hypersensitivity to adapalene or any other ingredients in Differin, it is important to avoid its use.

  2. Pregnancy and Nursing: The safety of Differin during pregnancy and breastfeeding has not been fully established. It is recommended to consult with a healthcare professional before using Differin if you are pregnant or breastfeeding.

  3. Severe Acne: Differin may not be sufficient for treating severe or cystic acne. In such cases, alternative treatments or a combination of therapies may be more appropriate. A healthcare professional can guide you on the best treatment options for your specific acne severity.

  4. Skin Conditions: If you have certain skin conditions, such as eczema, rosacea, or sunburned skin, it is advisable to avoid using Differin or use it with caution. Adapalene may exacerbate these conditions or cause further irritation.

  5. Medication Interactions: Inform your GP about any other topical or systemic medications you are using, as they may interact with Differin. This includes other acne treatments, such as benzoyl peroxide or topical antibiotics.

How to use Differin?

When using Differin, it is important to follow the instructions provided by your healthcare professional or indicated on the product packaging. Here is a general guideline on how to use Differin:

  1. Cleanse the Skin: Start by washing your face with a mild, non-medicated cleanser and patting it dry. Ensure that your skin is clean and free from dirt, oil, and makeup before applying Differin.

  2. Apply a Thin Layer: Take a pea-sized amount of Differin gel or cream on your fingertip. Gently apply a thin layer of Differin to the affected areas of the skin, such as the face, chest, or back, where acne lesions are present. Avoid applying it to unaffected areas.

  3. Avoid Sensitive Areas: Take care to avoid applying Differin near the eyes, lips, nostrils, and any areas of broken or irritated skin.

  4. Frequency of Use: Initially, it is recommended to use Differin once daily, preferably in the evening before bedtime. As your skin adjusts to the treatment, your healthcare professional may advise increasing the frequency to twice daily if necessary.

  5. Moisturize if Needed: If you experience dryness or irritation, you can apply a non-comedogenic moisturizer after Differin has absorbed into the skin. Wait for a few minutes after applying Differin to allow it to fully absorb before moisturizing.

  6. Sun Protection: Adapalene can increase skin sensitivity to sunlight, so it is crucial to apply sunscreen with at least SPF 30 or higher during the day and limit sun exposure. Protecting your skin from the sun helps prevent sunburn and potential skin damage.

  7. Be Patient and Consistent: It may take several weeks to see significant improvement in acne symptoms. It is important to be patient and continue using Differin as directed, even if you do not see immediate results. Consistent use is key to achieving the best outcomes.

Differin and other acne treatments

Using Differin in combination with other acne treatments can be an effective approach for managing acne. However, it is important to follow the guidance of a healthcare professional who can recommend the most suitable combination based on your specific needs. Here are a few commonly used combination approaches:

  1. Differin + Benzoyl Peroxide: Benzoyl peroxide is an over-the-counter acne treatment that helps to kill acne-causing bacteria and reduce inflammation. It can be used in conjunction with Differin to enhance the effectiveness of the treatment. However, it is advisable to use benzoyl peroxide in the morning and Differin in the evening to minimize the risk of skin irritation.

  2. Differin + Topical Antibiotics: Topical antibiotics, such as clindamycin or erythromycin, are often prescribed alongside Differin. Antibiotics help to reduce acne-causing bacteria and control inflammation. Applying Differin and the topical antibiotic at separate times of the day can help maximize their benefits.

  3. Differin + Oral Antibiotics: In some cases of moderate to severe acne, oral antibiotics may be prescribed along with Differin. Oral antibiotics, such as doxycycline or minocycline, work internally to target acne-causing bacteria and reduce inflammation. This combination is typically used for a limited period to avoid antibiotic resistance.

  4. Differin + Oral Contraceptives: For females with hormonal acne, combining Differin with oral contraceptives can be an effective treatment strategy. Oral contraceptives regulate hormone levels and help reduce the hormonal fluctuations that contribute to acne breakouts.

Differin: side effects and cautions

While Differin is generally well-tolerated, it can cause certain side effects and requires some cautions. Here are some common side effects and cautions associated with the use of Differin:

  1. Skin Irritation: In the initial stages of treatment, some individuals may experience mild skin irritation, redness, dryness, or peeling. This is a normal reaction as the skin adjusts to the medication. However, if the irritation is severe or persistent, it is advisable to consult a healthcare professional.

  2. Sun Sensitivity: Differin can increase skin sensitivity to sunlight, making your skin more prone to sunburn. It is crucial to apply sunscreen with at least SPF 30 or higher and limit sun exposure, especially during peak hours. Wearing protective clothing and using hats and sunglasses can also provide additional sun protection.

  3. Avoid Harsh Products: While using Differin, it is important to avoid using harsh or abrasive skincare products that may further irritate the skin. This includes harsh cleansers, scrubs, or products containing alcohol. Stick to gentle, non-comedogenic cleansers and moisturizers suitable for your skin type.

  4. Interaction with Other Products: Differin should not be used in combination with other retinoid-containing products unless specifically instructed by a healthcare professional. Using multiple retinoids simultaneously may increase the risk of skin irritation.

  5. Pregnancy and Breastfeeding: The safety of Differin during pregnancy and breastfeeding has not been fully established. It is advisable to consult with a healthcare professional before using Differin if you are pregnant or breastfeeding.

  6. Allergic Reactions: If you experience any signs of an allergic reaction, such as severe itching, swelling, rash, or difficulty breathing, discontinue use and seek immediate medical attention.

  7. Eye and Mucous Membrane Contact: Avoid getting Differin in contact with the eyes, lips, nostrils, and other mucous membranes, as it may cause irritation.

Pregnancy and breastfeeding

When it comes to using Differin (adapalene) during pregnancy and breastfeeding, it is important to exercise caution and consult with your doctor or pharmacist. While there is limited data on the use of Differin in pregnant and breastfeeding individuals, here are some general considerations:

Pregnancy:

  • Differin is classified as a Pregnancy Category C medication, which means it may not be safe for use during pregnancy.
  • Animal studies have shown some adverse effects on fetal development when high doses of adapalene were used.
  • It is generally recommended to avoid using Differin during pregnancy, especially during the first trimester when the fetal organs are forming.
  • If you become pregnant while using Differin, discontinue the medication and consult with your healthcare professional for further guidance.

    •  

    Breastfeeding:

  • The safety of Differin during breastfeeding is not well-established. There is limited information available on the extent of systemic absorption of adapalene and its potential transfer into breast milk.
  • It is advisable to consult with a healthcare professional before using Differin while breastfeeding.
  • Your healthcare professional can help weigh the potential risks and benefits and determine if the use of Differin is appropriate during this time.

    • Differin

    Frequently asked questions

    Differin contains the active ingredient adapalene, which is a type of retinoid. It works by normalizing the skin cell turnover process, preventing the formation of acne lesions. It helps unclog pores, reduces inflammation, and promotes the growth of new, healthy skin cells. Differin can improve acne symptoms, such as blackheads, whiteheads, pimples, and inflammation, leading to clearer skin over time.

    1. While Differin is generally well-tolerated, it can have some disadvantages:

    • Initial skin irritation: Some individuals may experience mild skin irritation, redness, dryness, or peeling when starting Differin. However, this is usually temporary and tends to improve as the skin adjusts to the treatment.
    • Sun sensitivity: Differin can increase skin sensitivity to sunlight, making it more prone to sunburn. It is important to use sunscreen and protect your skin from excessive sun exposure while using Differin.
    • Potential for dryness: Differin can cause dryness in some individuals, so it is important to use a non-comedogenic moisturizer if needed to keep the skin hydrated.

    Differin is a milder retinoid compared to prescription-strength retinoids such as tretinoin. While it belongs to the same class of medications, Differin is available over-the-counter and at lower concentrations. However, it can still be effective in treating mild to moderate acne when used as directed.

    During the initial stages of using Differin, some individuals may experience a temporary worsening of acne symptoms. This is known as a “purging” phase, where existing acne lesions come to the surface and new ones may form. However, this is typically followed by an improvement in acne over time. 

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    General Pharmaceutical Council's advice for online treatment

    The General Pharmaceutical Council (GPhC) and other UK health organisations have produced a handy guide to help people going online for medicines or treatment.
    Read the guideline here

    If you have a medical emergency do not use this service.
    Please contact your own GP, visit Accident and Emergency or call 999 or 111 immediately.

    HOW IT WORKS

    Three easy steps for your private treatment ...

    STEP 01

    Complete consultation questionnaire

    Complete consultation for your selected condition and order your medication. 

    Please answer the health questionnaire honestly, this will ensure that the medication you are requesting is right for you.

    STEP 02

    Prescriber approves

    The UK registered prescriber will review your questionnaire and approve your order. In some cases, the prescriber may specify a preferred treatment.

    STEP 03

    Delivered to your door

    Your treatment will be sent directly from our NHS online pharmacy, Online Chemist based in Norfolk.

    Delivery policy

    Service

    Expected Arrival

    Flat Fee
    Royal Mail Tracked 48 Usually takes between 2-4 working days, including Saturdays. Can rarely take up to 5 days. £3.80
    Royal Mail Tracked 24 1-3 day tracked service. Usually arrives the next day*, including Saturdays. £4.99
    Royal Mail Special Delivery by 1pm Guaranteed by the next working day before 1 pm. £7.50

    *Please keep in mind only orders placed before 12:00 pm on normal weekdays are dispatched on the same day. This is to give our clinicians and pharmacy staff enough time to check over the answers to your health questionnaire and issue and pack your medication before it is collected by the Royal Mail. The Royal Mail collects our orders at 3.30 pm. 

    Please note that orders placed after 12 pm on Friday and over the weekend will be processed on Monday.

    More details: Delivery & return policy