Phenergan tablets

Phenergan (promethazine) can interact with other medications, which may increase the risk of side effects or reduce the effectiveness of treatments. Some important considerations include:

• Central Nervous System Depressants (e.g., alcohol, benzodiazepines, opioids):

  • Combining Phenergan with other sedatives, such as alcohol, benzodiazepines (e.g., diazepam), or opioids (e.g., morphine), can enhance the sedative effect, leading to increased drowsiness, dizziness, and respiratory depression.

• Anticholinergic Medications (e.g., atropine, scopolamine, tricyclic antidepressants):

  • These can increase the likelihood of side effects like dry mouth, constipation, blurred vision, and urinary retention when taken with Phenergan.

• Antihypertensive Drugs (e.g., beta-blockers, ACE inhibitors):

  • Phenergan can sometimes cause low blood pressure, so combining it with blood pressure medications may lead to increased dizziness or fainting.

• Antidepressants (SSRIs, SNRIs):

  • Combining Phenergan with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) may increase the risk of serotonin syndrome, a rare but serious condition characterized by agitation, confusion, rapid heart rate, and increased body temperature.

• Anticonvulsants (e.g., phenytoin, carbamazepine):

  • Phenergan may interfere with the effectiveness of anticonvulsant medications and increase the risk of seizures.

• Other Antihistamines:

  • Using Phenergan alongside other antihistamines (e.g., cetirizine, loratadine) may increase the risk of side effects such as drowsiness, dry mouth, and dizziness.

It is essential to inform your doctor or pharmacist of all medications you are taking (prescription, over-the-counter, and herbal) to avoid potential interactions. They can provide guidance on safe combinations and adjust your treatment as needed.